Our reviews

We prepare, maintain and promote access to systematic reviews of interventions to treat or prevent common mental disorders.

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'Third wave' cognitive and behavioural therapies versus other psychological therapies for depression

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression

3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder (PTSD) in adults

Active placebos versus antidepressants for depression

Acupuncture for depression

Acupuncture for insomnia

Adverse effects of electroconvulsive therapy

Agomelatine versus other antidepressive agents for major depression

Alprazolam for depression

Alternating current cranial electrotherapy stimulation (CES) for depression

Amitriptyline for depression

Amitriptyline versus placebo for major depressive disorder

An overview of systematic reviews on mental health promotion, prevention, and treatment of common mental disorders for refugees, asylum seekers, and internally displaced persons

Antidepressant treatment for postnatal depression

Antidepressant treatment for postnatal depression

Antidepressants and benzodiazepines for panic disorder in adults

Antidepressants for anorexia nervosa

Antidepressants for depressed elderly

Antidepressants for depression in adults with HIV infection

Antidepressants for depression in physically ill people

Antidepressants for insomnia in adults

Antidepressants for major depression disorder in older people: a network meta-analysis

Antidepressants for preventing postnatal depression

Antidepressants plus benzodiazepines for adults with major depression

Antidepressants versus placebo for depression in primary care

Antidepressants versus placebo for generalised anxiety disorder (GAD)

Antidepressants versus placebo for panic disorder in adults

Antidepressants versus placebo for people with bulimia nervosa

Antidepressants versus placebo for the depressed elderly

Antidepressants versus psychological treatments and their combination for bulimia nervosa

Approaches for discontinuation versus continuation of long-term antidepressant use for depressive and anxiety disorders in adults

Aripiprazole alone or in combination for acute mania

Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders

Azapirones for generalized anxiety disorder

Azapirones versus placebo for panic disorder in adults

Behavioural activation therapy for anxiety disorders in adults

Behavioural activation therapy for depression in adults

Behavioural activation therapy for depression in adults with non-communicable diseases

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents

Behavioural and cognitive-behavioural therapy based self-help versus treatment as usual for depression in adults and adolescents

Behavioural therapies versus other psychological therapies for depression

Behavioural therapies versus treatment as usual for depression

Benzodiazepines versus placebo for panic disorder in adults

Breastfeeding interventions for preventing postpartum depression

Brexanolone and related neurosteroid GABA(A) positive allosteric modulators for postnatal depression

Brexpiprazole versus placebo or other antidepressive agents for treating depression

Citalopram versus other anti-depressive agents for depression

Client feedback in psychological therapy for children and adolescents with mental health problems

Cognitive behaviour therapy for chronic fatigue syndrome in adults

Cognitive behavioural therapy (CBT), third-wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents

Cognitive behavioural therapy and third wave approaches for anxiety and related disorders in older people

Cognitive behavioural therapy for anxiety disorders in children and adolescents

Cognitive behavioural therapy for anxiety disorders in children and adolescents

Cognitive or behavioural interventions (or both) to prevent or mitigate loneliness in adolescents, adults, and older adults

Collaborative care for depression and anxiety problems

Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)

Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia

Combined psychotherapy plus benzodiazepines for panic disorder

Community-based interventions for improving mental health in refugee children and adolescents in high-income countries

Comparative effectiveness of continuation and maintenance treatments for persistent depressive disorder in adults

Comparative efficacy and acceptability of pharmacological treatments for insomnia in adults: a systematic review and network meta-analysis

Consultation letters for medically unexplained physical symptoms in primary care

Continuation and maintenance treatments for depression in older people

Counselling for mental health and psychosocial problems in primary care

Couple and family therapies for post-traumatic stress disorder (PTSD)

Couple therapy for depression

Dance movement therapy for depression

Debriefing interventions for the prevention of psychological trauma in women following childbirth

Deprescribing of chronic benzodiazepine receptor agonists for insomnia in adults

Duloxetine versus other anti-depressive agents for depression

E-Health interventions for anxiety and depression in children and adolescents with long-term physical conditions

Early pharmacological interventions for acute traumatic stress symptoms: a network meta-analysis

Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD)

Early psychological interventions to treat acute traumatic stress symptoms

Electroconvulsive therapy for acute affective episodes in people with bipolar disorder

Electroconvulsive therapy for depression

Electroconvulsive therapy for preventing relapse and recurrence in bipolar disorder

Electroconvulsive therapy for preventing relapse and recurrence in people with depression

Electroconvulsive therapy for the depressed elderly

Enhanced care by generalists for functional somatic symptoms and disorders in primary care

Escitalopram versus other antidepressive agents for depression

Esketamine for treatment-resistant depression in adults

Eszopiclone for insomnia

Exercise for depression

Exercise for the treatment of anxiety in children and adolescents

Exercise in prevention and treatment of anxiety and depression among children and young people

Exercise therapy for chronic fatigue syndrome

Factors that influence participation in physical activity for anxiety or depression: a synthesis of qualitative evidence

Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of qualitative evidence

Family interventions for bipolar disorder

Family therapy approaches for anorexia nervosa

Family therapy for depression

First responder, clinician, and non-clinical support staff knowledge, attitudes, and behaviours towards people presenting for emergency care following self-harm: a mixed evidence synthesis

Fluoxetine versus other types of pharmacotherapy for depression

Fluvoxamine versus other anti-depressive agents for depression

Folate for depressive disorders

Government lockdown and mental health outcomes in the general population

Haloperidol alone or in combination for acute mania

Humanistic therapies versus other psychological therapies for depression

Humanistic therapies versus treatment as usual for depression

Hydroxyzine for generalised anxiety disorder

Individual psychological therapy in the outpatient treatment of adults with anorexia nervosa

Inositol for depressive disorders

Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders

Internet-based cognitive and behavioural therapies for post-traumatic stress disorder (PTSD) in adults

Interpersonal, cognitive analytic and other integrative therapies versus other psychological therapies for depression

Interventions (other than psychosocial, psychological and pharmacological) for treating postpartum depression

Interventions for helping people recognise early signs of recurrence in bipolar disorder

Interventions for helping people recognise early signs of recurrence in bipolar disorder

Interventions for helping people recognise early signs of recurrence in depression

Interventions for mood, anxiety disorders or self-harm in young offenders

Interventions for preventing eating disorders in children and adolescents

Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents

Interventions for preventing relapse or recurrence of major depressive disorder in adults in a primary care setting: a network meta-analysis

Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries

Interventions for self-harm in children and adolescents

Interventions for self-harm in children and adolescents

Interventions for the management of obesity in people with bipolar disorder

Interventions for vaginismus

Interventions to facilitate return to work in adults with adjustment disorders

Kava extract versus placebo for treating anxiety

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder

Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder

Lamotrigine in the maintenance treatment of bipolar disorder

Light therapy for non-seasonal depression

Light therapy for preventing seasonal affective disorder

Lithium for acute mania

Lithium for maintenance treatment of mood disorders

Lithium versus antidepressants in the long-term treatment of unipolar affective disorder

Low dosage tricyclic antidepressants for depression

Magnetic seizure therapy for treatment-resistant depression

Means restriction for the prevention of suicide by jumping

Means restriction for the prevention of suicide on roads

Means restriction for the prevention of suicide: generic protocol

Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults

Medicines for bipolar disorder in older people

Meditation therapy for anxiety disorders

Melatonin and agomelatine for preventing seasonal affective disorder

Melatonin for the prevention and treatment of jet lag

Mental Health First Aid as a tool for improving mental health and well-being

Milnacipran versus other antidepressive agents for depression

Mindfulness-based psychological interventions for improving mental well-being in medical students and junior doctors

Mirtazapine versus other antidepressive agents for depression

Morita therapy for anxiety disorders in adults

Multimedia-delivered cognitive behavioural therapy versus face-to-face cognitive behavioural therapy for depression in adults

Multiple session early psychological interventions for the prevention of post-traumatic stress disorder

Music therapy for depression

New generation antidepressants for depression in children and adolescents: a network meta-analysis

Newer anticonvulsants in the treatment of anxiety disorders

Newer generation antidepressants for depressive disorders in children and adolescents

Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults

Olanzapine alone or in combination for acute mania

Olanzapine in long-term treatment for bipolar disorder

Omega-3 fatty acid supplementation for depression in children and adolescents

Omega-3 fatty acids for bipolar disorder

Omega-3 fatty acids for depression in adults

Oxcarbazepine for acute affective episodes in bipolar disorder

Oxcarbazepine in the maintenance treatment of bipolar disorder

Paraprofessionals for anxiety and depressive disorders

Paroxetine versus other anti-depressive agents for depression

Passiflora for anxiety disorder

Perinatal internet-based cognitive behavioural therapy for preventing postnatal depression

Pharmacological and psychological interventions for depression in people with tuberculosis

Pharmacological interventions for adjustment disorders in adults

Pharmacological interventions for depression in adults with chronic hepatitis B or C

Pharmacological interventions for jet lag

Pharmacological interventions for preventing post-traumatic stress disorder (PTSD)

Pharmacological interventions for self-harm in adults

Pharmacological interventions for self-harm in adults

Pharmacological interventions for somatoform disorders in adults

Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease

Pharmacological interventions for the treatment of disordered and problem gambling

Pharmacological interventions for treatment-resistant depression in adults

Pharmacological treatment for psychotic depression

Pharmacological treatments in panic disorder in adults: a network meta-analysis

Pharmacotherapy and psychotherapy for body dysmorphic disorder

Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders

Pharmacotherapy for anxiety and comorbid alcohol use disorders

Pharmacotherapy for anxiety disorders in children and adolescents

Pharmacotherapy for dysthymia

Pharmacotherapy for post traumatic stress disorder (PTSD)

Pharmacotherapy for social anxiety disorder (SAnD)

Pharmacotherapy for trichotillomania

Pharmacy-based management for depression in adults

Postdischarge interventions for depression

Pre-deployment programmes for building resilience in military and frontline emergency service personnel

Present-centered therapy (PCT) for post-traumatic stress disorder (PTSD) in adults

Prevention of depression in adults with long-term physical conditions

Prevention of self-harm and suicide in young people up to the age of 25 in education settings

Prognostic models for predicting relapse or recurrence of major depressive disorder in adults

Psychodynamic therapies versus other psychological therapies for depression

Psychodynamic therapies versus treatment as usual for depression

Psychological and social interventions for the prevention of mental disorders in people living in low- and middle-income countries affected by humanitarian crises

Psychological and social interventions for the promotion of mental health in people living in low- and middle-income countries affected by humanitarian crises

Psychological debriefing for preventing post traumatic stress disorder (PTSD)

Psychological therapies for anxiety and depression in children and adolescents with long-term physical conditions

Psychological therapies for children and adolescents exposed to trauma

Psychological therapies for chronic post-traumatic stress disorder (PTSD) in adults

Psychological therapies for depression in older adults residing in long-term care settings

Psychological therapies for generalised anxiety disorder

Psychological therapies for major depressive disorder and prolonged grief in bereaved adults

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta-analysis

Psychological therapies for pathological and problem gambling

Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder

Psychological therapies for preventing seasonal affective disorder

Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease

Psychological therapies for the treatment of mental disorders in low- and middle-income countries affected by humanitarian crises

Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents

Psychological therapies for treatment-resistant depression in adults

Psychological therapies for women who experience intimate partner violence

Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults

Psychological treatments for bulimia nervosa and binging

Psychological treatments versus treatment as usual for obsessive compulsive disorder (OCD)

Psychological, social and welfare interventions for psychological health and well-being of torture survivors

Psychosocial and psychological interventions for treating postpartum depression

Psychosocial interventions by general practitioners

Psychosocial interventions for conversion and dissociative disorders in adults

Psychosocial interventions for prevention of psychological disorders in law enforcement officers

Psychosocial interventions for self-harm in adults

Psychosocial interventions for self-harm in adults

Psychostimulants for depression

Psychotherapeutic treatments for older depressed people

Psychotherapies for hypochondriasis

Ramelteon for insomnia

Reiki for depression and anxiety

Relaxation for depression

Remote non-pharmacologic interventions for sleep problems in adults during the COVID-19 pandemic

Remote non-pharmacologic interventions for sleep problems in healthcare workers during the COVID-19 pandemic

Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults

Repetitive transcranial magnetic stimulation for post-traumatic stress disorder in adults

Risperidone alone or in combination for acute mania

Risperidone in long-term treatment for bipolar disorder

Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults

S-adenosyl methionine (SAMe) for depression in adults

Screening and case finding instruments for depression

Second-generation antidepressants for preventing seasonal affective disorder in adults

Second-generation antidepressants for treatment of seasonal affective disorder

Second-generation antipsychotics for anxiety disorders

Second-generation antipsychotics for major depressive disorder and dysthymia

Second-generation antipsychotics for obsessive compulsive disorder

Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD)

Self-help and guided self-help for eating disorders

Self-report screening instruments for post-traumatic stress disorder (PTSD) in survivors of traumatic experiences

Sertraline versus other antidepressive agents for depression

Service users’ experiences of emergency care following an episode of self-harm: a mixed evidence synthesis

Short-term psychodynamic psychotherapies for common mental disorders

Specific psychological therapies versus other therapies or no treatment for severe and enduring anorexia nervosa

Sports and games for post-traumatic stress disorder (PTSD)

St John's wort for major depression

Strategies for managing sexual dysfunction induced by antidepressant medication

The diagnostic accuracy of widely used self-report questionnaires for detecting anxiety disorders in adults

The process and delivery of cognitive behavioural therapy (CBT) for depression in adults: a network meta-analysis

Therapeutic touch for anxiety disorders

Therapist-delivered distance cognitive behavioural therapy for anxiety disorders in adults

Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults

Tiagabine for acute affective episodes in bipolar disorder

Tiagabine in the maintenance treatment of bipolar disorder

Topiramate for acute affective episodes in bipolar disorder in adults

Transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder

Transcranial magnetic stimulation for treating depression

Transdiagnostic versus specific cognitive-behavioral treatments for adults with anxiety disorders

Tricyclic drugs for depression in children and adolescents

Tryptophan and 5-Hydroxytryptophan for depression

Valerian for anxiety disorders

Valproate for acute mania

Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder

Venlafaxine versus other anti-depressive agents for depression

Vilazodone for major depressive disorder in adults

Vortioxetine for depression in adults

Zaleplon for insomnia

Zolpidem for insomnia

Zopiclone for insomnia

Preventing occupational stress in healthcare workers

Prevention of suicide in university and other post-secondary educational settings

What are the best ways to help people with depression go back to work?

By subtopic:

Population (464)

Child & Adolescent (89)

Pharmacotherapy for anxiety disorders in children and adolescents

Acupuncture for insomnia

Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders

Amitriptyline for depression

Antidepressants versus psychological treatments and their combination for bulimia nervosa

Antidepressants versus placebo for people with bulimia nervosa

Antidepressants for anorexia nervosa

Aripiprazole alone or in combination for acute mania

Azapirones for generalized anxiety disorder

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents

Cognitive behavioural therapy for anxiety disorders in children and adolescents

Cognitive behavioural therapy for anxiety disorders in children and adolescents

Collaborative care for depression and anxiety problems

Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)

Counselling for mental health and psychosocial problems in primary care

Psychological and social interventions for the prevention of mental disorders in people living in low- and middle-income countries affected by humanitarian crises

Pharmacotherapy for trichotillomania

Pharmacotherapy for dysthymia

Pharmacological interventions for self-harm in adults

Cognitive behavioural therapy (CBT), third-wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents

Exercise in prevention and treatment of anxiety and depression among children and young people

Exercise for the treatment of anxiety in children and adolescents (protocol stage)

Family interventions for bipolar disorder

Family therapy for depression

Family therapy approaches for anorexia nervosa

Folate for depressive disorders

Haloperidol alone or in combination for acute mania

Inositol for depressive disorders

Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders

Internet-based cognitive and behavioural therapies for post-traumatic stress disorder (PTSD) in adults

Interventions for self-harm in children and adolescents

Interventions for the management of obesity in people with bipolar disorder (protocol stage)

Dance movement therapy for depression

Kava extract versus placebo for treating anxiety

Light therapy for non-seasonal depression

Lithium for maintenance treatment of mood disorders

Lithium for acute mania

Lithium versus antidepressants in the long-term treatment of unipolar affective disorder

Means restriction for the prevention of suicide: generic protocol (protocol stage)

Means restriction for the prevention of suicide by jumping

Means restriction for the prevention of suicide on roads

Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders

Pharmacotherapy for post traumatic stress disorder (PTSD)

Pharmacotherapy for social anxiety disorder (SAnD)

Pharmacotherapy and psychotherapy for body dysmorphic disorder

Melatonin for the prevention and treatment of jet lag

Multiple session early psychological interventions for the prevention of post-traumatic stress disorder

Newer anticonvulsants in the treatment of anxiety disorders (protocol stage)

Newer generation antidepressants for depressive disorders in children and adolescents

New generation antidepressants for depression in children and adolescents: a network meta-analysis

Olanzapine alone or in combination for acute mania

Olanzapine in long-term treatment for bipolar disorder

Omega-3 fatty acid supplementation for depression in children and adolescents (protocol stage)

Omega-3 fatty acids for bipolar disorder

Oxcarbazepine for acute affective episodes in bipolar disorder

Oxcarbazepine in the maintenance treatment of bipolar disorder

Pharmacological treatment for psychotic depression

Pharmacological interventions for the treatment of disordered and problem gambling

Interventions for preventing eating disorders in children and adolescents

Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder

Psychological therapies for children and adolescents exposed to trauma

Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents

Psychological, social and welfare interventions for psychological health and well-being of torture survivors

Psychosocial interventions by general practitioners

Psychosocial interventions for self-harm in adults

Relaxation for depression

Risperidone alone or in combination for acute mania

Risperidone in long-term treatment for bipolar disorder

S-adenosyl methionine (SAMe) for depression in adults

Second-generation antipsychotics for anxiety disorders

Second-generation antipsychotics for major depressive disorder and dysthymia

Second-generation antipsychotics for obsessive compulsive disorder

Self-help and guided self-help for eating disorders

Self-report screening instruments for post-traumatic stress disorder (PTSD) in survivors of traumatic experiences (protocol stage)

Specific psychological therapies versus other therapies or no treatment for severe and enduring anorexia nervosa (protocol stage)

Sports and games for post-traumatic stress disorder (PTSD)

Psychological therapies for the treatment of mental disorders in low- and middle-income countries affected by humanitarian crises

Psychosocial interventions for conversion and dissociative disorders in adults

Tiagabine in the maintenance treatment of bipolar disorder

Tiagabine for acute affective episodes in bipolar disorder

Topiramate for acute affective episodes in bipolar disorder in adults

Transcranial magnetic stimulation for treating depression

Transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder

Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents

Active placebos versus antidepressants for depression

Tricyclic drugs for depression in children and adolescents

Valproate for acute mania

Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder

'Third wave' cognitive and behavioural therapies versus other psychological therapies for depression

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression

Acupuncture for depression

Acupuncture for insomnia

Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders

Adverse effects of electroconvulsive therapy (protocol stage)

Agomelatine versus other antidepressive agents for major depression

Alprazolam for depression

Alternating current cranial electrotherapy stimulation (CES) for depression

Amitriptyline for depression

Amitriptyline versus placebo for major depressive disorder

Antidepressants for depression in adults with HIV infection

Antidepressant treatment for postnatal depression

Antidepressants and benzodiazepines for panic disorder in adults

Antidepressants versus psychological treatments and their combination for bulimia nervosa

Antidepressants versus placebo for people with bulimia nervosa

Antidepressants for anorexia nervosa

Antidepressants for depression in physically ill people

Antidepressants for insomnia in adults

Antidepressants versus placebo for panic disorder in adults

Second-generation antidepressants for preventing seasonal affective disorder in adults

Antidepressants plus benzodiazepines for adults with major depression

Antidepressants versus placebo for depression in primary care

Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease

Psychological therapies for treatment-resistant depression in adults

Pharmacological interventions for treatment-resistant depression in adults

Aripiprazole alone or in combination for acute mania

Azapirones for generalized anxiety disorder

Azapirones versus placebo for panic disorder in adults

Behavioural activation therapy for anxiety disorders in adults (protocol stage)

Behavioural activation therapy for depression in adults

Behavioural activation therapy for depression in adults with non-communicable diseases

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)

Behavioural and cognitive-behavioural therapy based self-help versus treatment as usual for depression in adults and adolescents (protocol stage)

Behavioural therapies versus other psychological therapies for depression

Behavioural therapies versus treatment as usual for depression (protocol stage)

Benzodiazepines versus placebo for panic disorder in adults

Brexanolone and related neurosteroid GABA(A) positive allosteric modulators for postnatal depression (protocol stage)

Brexpiprazole versus placebo or other antidepressive agents for treating depression (protocol stage)

Citalopram versus other anti-depressive agents for depression

Cognitive behaviour therapy for chronic fatigue syndrome in adults

Cognitive or behavioural interventions (or both) to prevent or mitigate loneliness in adolescents, adults, and older adults (protocol stage)

Collaborative care for depression and anxiety problems

Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)

Consultation letters for medically unexplained physical symptoms in primary care

Counselling for mental health and psychosocial problems in primary care

Couple and family therapies for post-traumatic stress disorder (PTSD)

Couple therapy for depression

Deprescribing of chronic benzodiazepine receptor agonists for insomnia in adults (protocol stage)

Psychological and social interventions for the prevention of mental disorders in people living in low- and middle-income countries affected by humanitarian crises

Prevention of depression in adults with long-term physical conditions

Pharmacotherapy for trichotillomania

Pharmacotherapy for dysthymia

Pharmacological interventions for self-harm in adults

Pharmacological interventions for self-harm in adults

Duloxetine versus other anti-depressive agents for depression

Early psychological interventions to treat acute traumatic stress symptoms

Electroconvulsive therapy for acute affective episodes in people with bipolar disorder (protocol stage)

Electroconvulsive therapy for depression (protocol stage)

Electroconvulsive therapy for preventing relapse and recurrence in bipolar disorder (protocol stage)

Electroconvulsive therapy for preventing relapse and recurrence in people with depression (protocol stage)

Enhanced care by generalists for functional somatic symptoms and disorders in primary care

Escitalopram versus other antidepressive agents for depression

Esketamine for treatment-resistant depression in adults (protocol stage)

Eszopiclone for insomnia

Exercise therapy for chronic fatigue syndrome

Exercise for depression

Family interventions for bipolar disorder

Family therapy for depression

Family therapy approaches for anorexia nervosa

Fluoxetine versus other types of pharmacotherapy for depression

Fluvoxamine versus other anti-depressive agents for depression

Folate for depressive disorders

Government lockdown and mental health outcomes in the general population (protocol stage)

Haloperidol alone or in combination for acute mania

Humanistic therapies versus other psychological therapies for depression (protocol stage)

Humanistic therapies versus treatment as usual for depression (protocol stage)

Hydroxyzine for generalised anxiety disorder

Interventions to facilitate return to work in adults with adjustment disorders

Inositol for depressive disorders

Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders

Internet-based cognitive and behavioural therapies for post-traumatic stress disorder (PTSD) in adults

Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults

Interpersonal, cognitive analytic and other integrative therapies versus other psychological therapies for depression (protocol stage)

Interventions for self-harm in children and adolescents

Interventions for helping people recognise early signs of recurrence in bipolar disorder

Interventions for helping people recognise early signs of recurrence in depression (protocol stage)

Interventions for preventing relapse or recurrence of major depressive disorder in adults in a primary care setting: a network meta-analysis (protocol stage)

Interventions for the management of obesity in people with bipolar disorder (protocol stage)

Interventions for vaginismus

Dance movement therapy for depression

Magnetic seizure therapy for treatment-resistant depression

Kava extract versus placebo for treating anxiety

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder

Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder

Light therapy for preventing seasonal affective disorder

Light therapy for non-seasonal depression

Lithium for maintenance treatment of mood disorders

Lithium for acute mania

Lithium versus antidepressants in the long-term treatment of unipolar affective disorder

Low dosage tricyclic antidepressants for depression

Means restriction for the prevention of suicide: generic protocol (protocol stage)

Means restriction for the prevention of suicide by jumping

Means restriction for the prevention of suicide on roads

Pharmacological interventions for somatoform disorders in adults

Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders

Pharmacotherapy for post traumatic stress disorder (PTSD)

Pharmacotherapy for social anxiety disorder (SAnD)

Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease

Pharmacotherapy for anxiety and comorbid alcohol use disorders

Pharmacotherapy and psychotherapy for body dysmorphic disorder

Pharmacological interventions for preventing post-traumatic stress disorder (PTSD)

Meditation therapy for anxiety disorders

Melatonin and agomelatine for preventing seasonal affective disorder

Melatonin for the prevention and treatment of jet lag

Mental Health First Aid as a tool for improving mental health and well-being (protocol stage)

Milnacipran versus other antidepressive agents for depression

Mirtazapine versus other antidepressive agents for depression

Morita therapy for anxiety disorders in adults

Multimedia-delivered cognitive behavioural therapy versus face-to-face cognitive behavioural therapy for depression in adults (protocol stage)

Multiple session early psychological interventions for the prevention of post-traumatic stress disorder

Music therapy for depression

Newer anticonvulsants in the treatment of anxiety disorders (protocol stage)

Olanzapine alone or in combination for acute mania

Olanzapine in long-term treatment for bipolar disorder

Omega-3 fatty acids for bipolar disorder

Omega-3 fatty acids for depression in adults

Individual psychological therapy in the outpatient treatment of adults with anorexia nervosa

Oxcarbazepine for acute affective episodes in bipolar disorder

Oxcarbazepine in the maintenance treatment of bipolar disorder

Paroxetine versus other anti-depressive agents for depression

Passiflora for anxiety disorder

Pharmacy-based management for depression in adults

Pharmacological and psychological interventions for depression in people with tuberculosis (protocol stage)

Pharmacological interventions for adjustment disorders in adults (protocol stage)

Pharmacological interventions for depression in adults with chronic hepatitis B or C (protocol stage)

Pharmacological interventions for jet lag (protocol stage)

Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Pharmacological treatment for psychotic depression

Pharmacological interventions for the treatment of disordered and problem gambling

Pharmacological treatments in panic disorder in adults: a network meta-analysis (protocol stage)

Postdischarge interventions for depression (protocol stage)

Prognostic models for predicting relapse or recurrence of major depressive disorder in adults

Present-centered therapy (PCT) for post-traumatic stress disorder (PTSD) in adults

Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries

Psychodynamic therapies versus other psychological therapies for depression (protocol stage)

Psychodynamic therapies versus treatment as usual for depression (protocol stage)

Psychological debriefing for preventing post traumatic stress disorder (PTSD)

Psychological therapies for chronic post-traumatic stress disorder (PTSD) in adults

Psychological therapies for pathological and problem gambling

Psychological therapies for generalised anxiety disorder

Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder

Psychological therapies for preventing seasonal affective disorder

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta-analysis

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults

Psychological treatments versus treatment as usual for obsessive compulsive disorder (OCD)

Psychological treatments for bulimia nervosa and binging

Psychological, social and welfare interventions for psychological health and well-being of torture survivors

Psychosocial and psychological interventions for treating postpartum depression

Psychosocial interventions by general practitioners

Psychosocial interventions for self-harm in adults

Psychosocial interventions for self-harm in adults

Psychostimulants for depression

Psychotherapies for hypochondriasis

Combined psychotherapy plus benzodiazepines for panic disorder

Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia

Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Ramelteon for insomnia (protocol stage)

Reiki for depression and anxiety

Relaxation for depression

Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults

Repetitive transcranial magnetic stimulation for post-traumatic stress disorder in adults (protocol stage)

Risperidone alone or in combination for acute mania

Risperidone in long-term treatment for bipolar disorder

S-adenosyl methionine (SAMe) for depression in adults

Screening and case finding instruments for depression

Second-generation antidepressants for treatment of seasonal affective disorder

Second-generation antipsychotics for anxiety disorders

Second-generation antipsychotics for major depressive disorder and dysthymia

Second-generation antipsychotics for obsessive compulsive disorder

Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD)

Self-help and guided self-help for eating disorders

Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults

Self-report screening instruments for post-traumatic stress disorder (PTSD) in survivors of traumatic experiences (protocol stage)

Sertraline versus other antidepressive agents for depression

Short-term psychodynamic psychotherapies for common mental disorders

Specific psychological therapies versus other therapies or no treatment for severe and enduring anorexia nervosa (protocol stage)

Sports and games for post-traumatic stress disorder (PTSD)

St John's wort for major depression

Strategies for managing sexual dysfunction induced by antidepressant medication

Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults

Psychological therapies for the treatment of mental disorders in low- and middle-income countries affected by humanitarian crises

Paraprofessionals for anxiety and depressive disorders

The process and delivery of cognitive behavioural therapy (CBT) for depression in adults: a network meta-analysis (protocol stage)

Psychosocial interventions for conversion and dissociative disorders in adults

Therapeutic touch for anxiety disorders

Therapist-delivered distance cognitive behavioural therapy for anxiety disorders in adults (protocol stage)

Tiagabine in the maintenance treatment of bipolar disorder

Tiagabine for acute affective episodes in bipolar disorder

Topiramate for acute affective episodes in bipolar disorder in adults

Transcranial magnetic stimulation for treating depression

Transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder

Transdiagnostic versus specific cognitive-behavioral treatments for adults with anxiety disorders (protocol stage)

Active placebos versus antidepressants for depression

Tryptophan and 5-Hydroxytryptophan for depression

Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults

Valerian for anxiety disorders

Valproate for acute mania

Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder

Venlafaxine versus other anti-depressive agents for depression (protocol stage)

Vortioxetine for depression in adults

What are the best ways to help people with depression go back to work?

Zaleplon for insomnia (protocol stage)

Zolpidem for insomnia (protocol stage)

Zopiclone for insomnia (protocol stage)

Exclusively child and/or adolescent poopulation (16)

Pharmacotherapy for anxiety disorders in children and adolescents

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents

Client feedback in psychological therapy for children and adolescents with mental health problems

Cognitive behavioural therapy for anxiety disorders in children and adolescents

E-Health interventions for anxiety and depression in children and adolescents with long-term physical conditions

Cognitive behavioural therapy (CBT), third-wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents

Exercise in prevention and treatment of anxiety and depression among children and young people

Newer generation antidepressants for depressive disorders in children and adolescents

New generation antidepressants for depression in children and adolescents: a network meta-analysis

Interventions for preventing eating disorders in children and adolescents

Psychological therapies for anxiety and depression in children and adolescents with long-term physical conditions

Psychological therapies for children and adolescents exposed to trauma

Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents

Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents

Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents

Tricyclic drugs for depression in children and adolescents

Older people (125)

Acupuncture for insomnia

Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders

Amitriptyline for depression

Amitriptyline versus placebo for major depressive disorder

Antidepressants versus psychological treatments and their combination for bulimia nervosa

Antidepressants versus placebo for people with bulimia nervosa

Antidepressants versus placebo for the depressed elderly

Antidepressants for anorexia nervosa

Antidepressants for depressed elderly

Antidepressants for depression in physically ill people

Antidepressants for major depression disorder in older people: a network meta-analysis (protocol stage)

Antidepressants versus placebo for panic disorder in adults

Antidepressants plus benzodiazepines for adults with major depression

Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease

Azapirones for generalized anxiety disorder

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)

Benzodiazepines versus placebo for panic disorder in adults

Citalopram versus other anti-depressive agents for depression

Cognitive behaviour therapy for chronic fatigue syndrome in adults

Cognitive behavioural therapy and third wave approaches for anxiety and related disorders in older people (protocol stage)

Collaborative care for depression and anxiety problems

Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)

Consultation letters for medically unexplained physical symptoms in primary care

Counselling for mental health and psychosocial problems in primary care

Pharmacotherapy for trichotillomania

Pharmacotherapy for dysthymia

Pharmacological interventions for self-harm in adults

Duloxetine versus other anti-depressive agents for depression

Early psychological interventions to treat acute traumatic stress symptoms

Electroconvulsive therapy for the depressed elderly

Enhanced care by generalists for functional somatic symptoms and disorders in primary care

Escitalopram versus other antidepressive agents for depression

Exercise therapy for chronic fatigue syndrome

Exercise for depression

Family interventions for bipolar disorder

Family therapy for depression

Family therapy approaches for anorexia nervosa

Fluoxetine versus other types of pharmacotherapy for depression

Fluvoxamine versus other anti-depressive agents for depression

Folate for depressive disorders

Haloperidol alone or in combination for acute mania

Hydroxyzine for generalised anxiety disorder

Interventions to facilitate return to work in adults with adjustment disorders

Inositol for depressive disorders

Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults

Interventions for self-harm in children and adolescents

Interventions for helping people recognise early signs of recurrence in bipolar disorder

Interventions for helping people recognise early signs of recurrence in depression (protocol stage)

Interventions for vaginismus

Dance movement therapy for depression

Kava extract versus placebo for treating anxiety

Light therapy for non-seasonal depression

Lithium for maintenance treatment of mood disorders

Lithium for acute mania

Lithium versus antidepressants in the long-term treatment of unipolar affective disorder

Continuation and maintenance treatments for depression in older people

Low dosage tricyclic antidepressants for depression

Means restriction for the prevention of suicide: generic protocol (protocol stage)

Means restriction for the prevention of suicide by jumping

Means restriction for the prevention of suicide on roads

Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders

Pharmacotherapy for post traumatic stress disorder (PTSD)

Pharmacotherapy for social anxiety disorder (SAnD)

Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease

Pharmacotherapy and psychotherapy for body dysmorphic disorder

Medicines for bipolar disorder in older people (protocol stage)

Meditation therapy for anxiety disorders

Melatonin for the prevention and treatment of jet lag

Milnacipran versus other antidepressive agents for depression

Mirtazapine versus other antidepressive agents for depression

Multiple session early psychological interventions for the prevention of post-traumatic stress disorder

Music therapy for depression

Newer anticonvulsants in the treatment of anxiety disorders (protocol stage)

Olanzapine alone or in combination for acute mania

Olanzapine in long-term treatment for bipolar disorder

Omega-3 fatty acids for bipolar disorder

Oxcarbazepine for acute affective episodes in bipolar disorder

Oxcarbazepine in the maintenance treatment of bipolar disorder

Passiflora for anxiety disorder

Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Pharmacological treatment for psychotic depression

Psychological debriefing for preventing post traumatic stress disorder (PTSD)

Psychological therapies for chronic post-traumatic stress disorder (PTSD) in adults

Psychological therapies for depression in older adults residing in long-term care settings (protocol stage)

Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder

Psychological treatments for bulimia nervosa and binging

Psychological, social and welfare interventions for psychological health and well-being of torture survivors

Psychosocial interventions by general practitioners

Psychosocial interventions for self-harm in adults

Psychostimulants for depression

Psychotherapeutic treatments for older depressed people

Combined psychotherapy plus benzodiazepines for panic disorder

Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia

Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Relaxation for depression

Risperidone alone or in combination for acute mania

Risperidone in long-term treatment for bipolar disorder

S-adenosyl methionine (SAMe) for depression in adults

Screening and case finding instruments for depression

Second-generation antipsychotics for anxiety disorders

Second-generation antipsychotics for major depressive disorder and dysthymia

Second-generation antipsychotics for obsessive compulsive disorder

Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD)

Self-help and guided self-help for eating disorders

Self-report screening instruments for post-traumatic stress disorder (PTSD) in survivors of traumatic experiences (protocol stage)

Sertraline versus other antidepressive agents for depression

Short-term psychodynamic psychotherapies for common mental disorders

Sports and games for post-traumatic stress disorder (PTSD)

St John's wort for major depression

Strategies for managing sexual dysfunction induced by antidepressant medication

Paraprofessionals for anxiety and depressive disorders

Psychosocial interventions for conversion and dissociative disorders in adults

Therapeutic touch for anxiety disorders

Therapist-delivered distance cognitive behavioural therapy for anxiety disorders in adults (protocol stage)

Tiagabine in the maintenance treatment of bipolar disorder

Tiagabine for acute affective episodes in bipolar disorder

Topiramate for acute affective episodes in bipolar disorder in adults

Transcranial magnetic stimulation for treating depression

Transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder

Active placebos versus antidepressants for depression

Tryptophan and 5-Hydroxytryptophan for depression

Valerian for anxiety disorders

Valproate for acute mania

Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder

What are the best ways to help people with depression go back to work?

Specialist populations (19)

An overview of systematic reviews on mental health promotion, prevention, and treatment of common mental disorders for refugees, asylum seekers, and internally displaced persons

Antidepressants for preventing postnatal depression

Antidepressant treatment for postnatal depression

Breastfeeding interventions for preventing postpartum depression (protocol stage)

Debriefing interventions for the prevention of psychological trauma in women following childbirth

Pre-deployment programmes for building resilience in military and frontline emergency service personnel

Interventions (other than psychosocial, psychological and pharmacological) for treating postpartum depression (protocol stage)

Interventions for mood, anxiety disorders or self-harm in young offenders (protocol stage)

Pharmacotherapy for anxiety and comorbid alcohol use disorders

Community-based interventions for improving mental health in refugee children and adolescents in high-income countries

Mindfulness-based psychological interventions for improving mental well-being in medical students and junior doctors

Perinatal internet-based cognitive behavioural therapy for preventing postnatal depression (protocol stage)

Preventing occupational stress in healthcare workers

Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries

Psychological therapies for major depressive disorder and prolonged grief in bereaved adults (protocol stage)

Psychological therapies for women who experience intimate partner violence

Psychosocial interventions for prevention of psychological disorders in law enforcement officers

Remote non-pharmacologic interventions for sleep problems in adults during the COVID-19 pandemic (protocol stage)

Remote non-pharmacologic interventions for sleep problems in healthcare workers during the COVID-19 pandemic (protocol stage)

Intervention (269)

All pharmacological (31)

Pharmacotherapy for anxiety disorders in children and adolescents

Antidepressants and benzodiazepines for panic disorder in adults

Pharmacological interventions for treatment-resistant depression in adults

Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)

Comparative efficacy and acceptability of pharmacological treatments for insomnia in adults: a systematic review and network meta-analysis (protocol stage)

Deprescribing of chronic benzodiazepine receptor agonists for insomnia in adults (protocol stage)

Pharmacotherapy for trichotillomania

Pharmacotherapy for dysthymia

Pharmacological interventions for self-harm in adults

Pharmacological interventions for self-harm in adults

Early pharmacological interventions for acute traumatic stress symptoms: a network meta-analysis (protocol stage)

Interventions for self-harm in children and adolescents

Interventions for self-harm in children and adolescents

Continuation and maintenance treatments for depression in older people

Comparative effectiveness of continuation and maintenance treatments for persistent depressive disorder in adults

Pharmacological interventions for somatoform disorders in adults

Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders

Pharmacotherapy for post traumatic stress disorder (PTSD)

Pharmacotherapy for social anxiety disorder (SAnD)

Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease

Pharmacotherapy for anxiety and comorbid alcohol use disorders

Pharmacotherapy and psychotherapy for body dysmorphic disorder

Pharmacological interventions for preventing post-traumatic stress disorder (PTSD)

Medicines for bipolar disorder in older people (protocol stage)

Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD)

Pharmacological interventions for adjustment disorders in adults (protocol stage)

Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Pharmacological treatment for psychotic depression

Pharmacological interventions for the treatment of disordered and problem gambling

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults

Psychosocial interventions for self-harm in adults

Antidepressants (49)

All antidepressants (25)

Antidepressants for depression in adults with HIV infection

Antidepressants for preventing postnatal depression

Antidepressant treatment for postnatal depression

Antidepressants versus psychological treatments and their combination for bulimia nervosa

Antidepressants versus placebo for people with bulimia nervosa

Antidepressants versus placebo for the depressed elderly

Antidepressants for anorexia nervosa

Antidepressants for depressed elderly

Antidepressants for depression in physically ill people

Antidepressants for insomnia in adults

Antidepressants for major depression disorder in older people: a network meta-analysis (protocol stage)

Antidepressants versus placebo for panic disorder in adults

Antidepressant treatment for postnatal depression

Antidepressants plus benzodiazepines for adults with major depression

Antidepressants versus placebo for depression in primary care

Antidepressants versus placebo for generalised anxiety disorder (GAD) (protocol stage)

Benzodiazepines versus placebo for panic disorder in adults

Brexpiprazole versus placebo or other antidepressive agents for treating depression (protocol stage)

Lithium versus antidepressants in the long-term treatment of unipolar affective disorder

Pharmacological and psychological interventions for depression in people with tuberculosis (protocol stage)

Pharmacological treatments in panic disorder in adults: a network meta-analysis (protocol stage)

Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia

Approaches for discontinuation versus continuation of long-term antidepressant use for depressive and anxiety disorders in adults

Active placebos versus antidepressants for depression

Vilazodone for major depressive disorder in adults (protocol stage)

Other antidepressants (2)

Milnacipran versus other antidepressive agents for depression

Mirtazapine versus other antidepressive agents for depression

Agomelatine versus other antidepressive agents for major depression

Second-generation antidepressants for preventing seasonal affective disorder in adults

Citalopram versus other anti-depressive agents for depression

Duloxetine versus other anti-depressive agents for depression

Escitalopram versus other antidepressive agents for depression

Fluoxetine versus other types of pharmacotherapy for depression

Fluvoxamine versus other anti-depressive agents for depression

Light therapy for preventing seasonal affective disorder

Melatonin and agomelatine for preventing seasonal affective disorder

Newer generation antidepressants for depressive disorders in children and adolescents

New generation antidepressants for depression in children and adolescents: a network meta-analysis

Paroxetine versus other anti-depressive agents for depression

Psychological therapies for preventing seasonal affective disorder

Second-generation antidepressants for treatment of seasonal affective disorder

Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD)

Sertraline versus other antidepressive agents for depression

Venlafaxine versus other anti-depressive agents for depression (protocol stage)

Vortioxetine for depression in adults

Amitriptyline for depression

Amitriptyline versus placebo for major depressive disorder

Low dosage tricyclic antidepressants for depression

Tricyclic drugs for depression in children and adolescents

Antipsychotics (9)

Aripiprazole alone or in combination for acute mania

Haloperidol alone or in combination for acute mania

Olanzapine alone or in combination for acute mania

Olanzapine in long-term treatment for bipolar disorder

Risperidone alone or in combination for acute mania

Risperidone in long-term treatment for bipolar disorder

Second-generation antipsychotics for anxiety disorders

Second-generation antipsychotics for major depressive disorder and dysthymia

Second-generation antipsychotics for obsessive compulsive disorder

Anxiolytics (10)

Azapirones for generalized anxiety disorder

Azapirones versus placebo for panic disorder in adults

Pharmacological treatments in panic disorder in adults: a network meta-analysis (protocol stage)

Benzodiazepines (6)

Alprazolam for depression

Antidepressants versus placebo for panic disorder in adults

Antidepressants plus benzodiazepines for adults with major depression

Benzodiazepines versus placebo for panic disorder in adults

Pharmacological treatments in panic disorder in adults: a network meta-analysis (protocol stage)

Combined psychotherapy plus benzodiazepines for panic disorder

Diphenylmethane derivatives (1)

Hydroxyzine for generalised anxiety disorder

Mood stablisers (3)

Lithium for maintenance treatment of mood disorders

Lithium for acute mania

Lithium versus antidepressants in the long-term treatment of unipolar affective disorder

Physical treatments (13)

Adverse effects of electroconvulsive therapy (protocol stage)

Alternating current cranial electrotherapy stimulation (CES) for depression

Electroconvulsive therapy for the depressed elderly

Electroconvulsive therapy for acute affective episodes in people with bipolar disorder (protocol stage)

Electroconvulsive therapy for depression (protocol stage)

Electroconvulsive therapy for preventing relapse and recurrence in bipolar disorder (protocol stage)

Electroconvulsive therapy for preventing relapse and recurrence in people with depression (protocol stage)

Magnetic seizure therapy for treatment-resistant depression

Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults

Repetitive transcranial magnetic stimulation for post-traumatic stress disorder in adults (protocol stage)

Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults

Transcranial magnetic stimulation for treating depression

Transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder

Psychostimulants (1)

Psychostimulants for depression

Psychotherapies (86)

General psychotherapies (51)

Antidepressants versus psychological treatments and their combination for bulimia nervosa

Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease

Psychological therapies for treatment-resistant depression in adults

Pharmacological interventions for treatment-resistant depression in adults

Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)

Counselling for mental health and psychosocial problems in primary care

Couple and family therapies for post-traumatic stress disorder (PTSD)

Couple therapy for depression

Psychological and social interventions for the prevention of mental disorders in people living in low- and middle-income countries affected by humanitarian crises

Pharmacological interventions for self-harm in adults

E-Health interventions for anxiety and depression in children and adolescents with long-term physical conditions

Early psychological interventions to treat acute traumatic stress symptoms

Family interventions for bipolar disorder

Family therapy for depression

Family therapy approaches for anorexia nervosa

Interventions for self-harm in children and adolescents

Interventions for self-harm in children and adolescents

Continuation and maintenance treatments for depression in older people

Pharmacotherapy and psychotherapy for body dysmorphic disorder

Multiple session early psychological interventions for the prevention of post-traumatic stress disorder

Individual psychological therapy in the outpatient treatment of adults with anorexia nervosa

Pharmacological and psychological interventions for depression in people with tuberculosis (protocol stage)

Present-centered therapy (PCT) for post-traumatic stress disorder (PTSD) in adults

Psychological and social interventions for the promotion of mental health in people living in low- and middle-income countries affected by humanitarian crises (protocol stage)

Psychological debriefing for preventing post traumatic stress disorder (PTSD)

Psychological therapies for chronic post-traumatic stress disorder (PTSD) in adults

Psychological therapies for depression in older adults residing in long-term care settings (protocol stage)

Psychological therapies for major depressive disorder and prolonged grief in bereaved adults (protocol stage)

Psychological therapies for pathological and problem gambling

Psychological therapies for generalised anxiety disorder

Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder

Psychological therapies for children and adolescents exposed to trauma

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta-analysis

Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults

Psychological treatments versus treatment as usual for obsessive compulsive disorder (OCD)

Psychological treatments for bulimia nervosa and binging

Psychological, social and welfare interventions for psychological health and well-being of torture survivors

Psychosocial and psychological interventions for treating postpartum depression

Psychosocial interventions by general practitioners

Psychosocial interventions for self-harm in adults

Psychosocial interventions for prevention of psychological disorders in law enforcement officers

Psychotherapeutic treatments for older depressed people

Psychotherapies for hypochondriasis

Combined psychotherapy plus benzodiazepines for panic disorder

Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia

Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Specific psychological therapies versus other therapies or no treatment for severe and enduring anorexia nervosa (protocol stage)

Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults

Psychological therapies for the treatment of mental disorders in low- and middle-income countries affected by humanitarian crises

Psychosocial interventions for conversion and dissociative disorders in adults

Behavioural (9)

Behavioural activation therapy for anxiety disorders in adults (protocol stage)

Behavioural activation therapy for depression in adults

Behavioural activation therapy for depression in adults with non-communicable diseases

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents

Behavioural therapies versus other psychological therapies for depression

Behavioural therapies versus treatment as usual for depression (protocol stage)

Multimedia-delivered cognitive behavioural therapy versus face-to-face cognitive behavioural therapy for depression in adults (protocol stage)

Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults

Cognitive behavioural (CBT) (15)

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents

Cognitive behaviour therapy for chronic fatigue syndrome in adults

Cognitive behavioural therapy and third wave approaches for anxiety and related disorders in older people (protocol stage)

Cognitive behavioural therapy for anxiety disorders in children and adolescents

Cognitive behavioural therapy for anxiety disorders in children and adolescents

Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults

Multimedia-delivered cognitive behavioural therapy versus face-to-face cognitive behavioural therapy for depression in adults (protocol stage)

Perinatal internet-based cognitive behavioural therapy for preventing postnatal depression (protocol stage)

Psychological therapies for pathological and problem gambling

Psychological therapies for women who experience intimate partner violence

Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults

The process and delivery of cognitive behavioural therapy (CBT) for depression in adults: a network meta-analysis (protocol stage)

Therapist-delivered distance cognitive behavioural therapy for anxiety disorders in adults (protocol stage)

Transdiagnostic versus specific cognitive-behavioral treatments for adults with anxiety disorders (protocol stage)

Humanistic therapies versus other psychological therapies for depression (protocol stage)

Humanistic therapies versus treatment as usual for depression (protocol stage)

Integrative (2)

Interpersonal, cognitive analytic and other integrative therapies versus other psychological therapies for depression (protocol stage)

Psychological therapies for pathological and problem gambling

Third wave CBT (3)

'Third wave' cognitive and behavioural therapies versus other psychological therapies for depression

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression

Psychological therapies for pathological and problem gambling

Psychodynamic (4)

Psychodynamic therapies versus other psychological therapies for depression (protocol stage)

Psychodynamic therapies versus treatment as usual for depression (protocol stage)

Psychological therapies for pathological and problem gambling

Short-term psychodynamic psychotherapies for common mental disorders

Other pharmacological interventions (12)

Brexanolone and related neurosteroid GABA(A) positive allosteric modulators for postnatal depression (protocol stage)

Esketamine for treatment-resistant depression in adults (protocol stage)

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder

Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder

Lamotrigine in the maintenance treatment of bipolar disorder

Oxcarbazepine for acute affective episodes in bipolar disorder

Oxcarbazepine in the maintenance treatment of bipolar disorder

Tiagabine in the maintenance treatment of bipolar disorder

Tiagabine for acute affective episodes in bipolar disorder

Topiramate for acute affective episodes in bipolar disorder in adults

Valproate for acute mania

Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder

Complementary medicine (19)

Folate for depressive disorders

Inositol for depressive disorders

Kava extract versus placebo for treating anxiety

Light therapy for non-seasonal depression

Meditation therapy for anxiety disorders

Melatonin for the prevention and treatment of jet lag

Omega-3 fatty acid supplementation for depression in children and adolescents (protocol stage)

Omega-3 fatty acids for bipolar disorder

Omega-3 fatty acids for depression in adults

Passiflora for anxiety disorder

Pharmacological interventions for jet lag (protocol stage)

Reiki for depression and anxiety

Relaxation for depression

St John's wort for major depression

Therapeutic touch for anxiety disorders

Tryptophan and 5-Hydroxytryptophan for depression

Valerian for anxiety disorders

Specific interventions (2)

Acupuncture (2)

Acupuncture for depression

Acupuncture for insomnia

Exercise therapy for chronic fatigue syndrome

Exercise for depression

Exercise in prevention and treatment of anxiety and depression among children and young people

Exercise for the treatment of anxiety in children and adolescents (protocol stage)

Behavioural and cognitive-behavioural therapy based self-help versus treatment as usual for depression in adults and adolescents (protocol stage)

Breastfeeding interventions for preventing postpartum depression (protocol stage)

Cognitive or behavioural interventions (or both) to prevent or mitigate loneliness in adolescents, adults, and older adults (protocol stage)

Consultation letters for medically unexplained physical symptoms in primary care

Government lockdown and mental health outcomes in the general population (protocol stage)

Internet-based cognitive and behavioural therapies for post-traumatic stress disorder (PTSD) in adults

Interventions (other than psychosocial, psychological and pharmacological) for treating postpartum depression (protocol stage)

Interventions for helping people recognise early signs of recurrence in depression (protocol stage)

Interventions for preventing relapse or recurrence of major depressive disorder in adults in a primary care setting: a network meta-analysis (protocol stage)

Interventions for the management of obesity in people with bipolar disorder (protocol stage)

Dance movement therapy for depression

Means restriction for the prevention of suicide: generic protocol (protocol stage)

Means restriction for the prevention of suicide by jumping

Means restriction for the prevention of suicide on roads

Mindfulness-based psychological interventions for improving mental well-being in medical students and junior doctors

Morita therapy for anxiety disorders in adults

Music therapy for depression

Prevention of self-harm and suicide in young people up to the age of 25 in education settings (protocol stage)

Remote non-pharmacologic interventions for sleep problems in adults during the COVID-19 pandemic (protocol stage)

Self-help and guided self-help for eating disorders

Sports and games for post-traumatic stress disorder (PTSD)

setting/service delivery based (11)

Client feedback in psychological therapy for children and adolescents with mental health problems

Collaborative care for depression and anxiety problems

Enhanced care by generalists for functional somatic symptoms and disorders in primary care

Pre-deployment programmes for building resilience in military and frontline emergency service personnel

Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders

Mental Health First Aid as a tool for improving mental health and well-being (protocol stage)

Pharmacy-based management for depression in adults

Prevention of self-harm and suicide in young people up to the age of 25 in education settings (protocol stage)

Psychosocial interventions by general practitioners

Paraprofessionals for anxiety and depressive disorders

Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults

Condition (275)

Adjustment disorders (3)

Antidepressants for depression in physically ill people

Interventions to facilitate return to work in adults with adjustment disorders

Pharmacological interventions for adjustment disorders in adults (protocol stage)

Anxiety disorders (75)

All anxiety disorders (31)

Pharmacotherapy for anxiety disorders in children and adolescents

Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders

Behavioural activation therapy for anxiety disorders in adults (protocol stage)

Cognitive behavioural therapy and third wave approaches for anxiety and related disorders in older people (protocol stage)

Cognitive behavioural therapy for anxiety disorders in children and adolescents

Cognitive behavioural therapy for anxiety disorders in children and adolescents

Collaborative care for depression and anxiety problems

Exercise in prevention and treatment of anxiety and depression among children and young people

Exercise for the treatment of anxiety in children and adolescents (protocol stage)

Factors that influence participation in physical activity for anxiety or depression: a synthesis of qualitative evidence (protocol stage)

Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults

Interventions for mood, anxiety disorders or self-harm in young offenders (protocol stage)

Kava extract versus placebo for treating anxiety

Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders

Pharmacotherapy for anxiety and comorbid alcohol use disorders

Meditation therapy for anxiety disorders

Morita therapy for anxiety disorders in adults

Newer anticonvulsants in the treatment of anxiety disorders (protocol stage)

Passiflora for anxiety disorder

Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries

Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Second-generation antipsychotics for anxiety disorders

Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults

Short-term psychodynamic psychotherapies for common mental disorders

The diagnostic accuracy of widely used self-report questionnaires for detecting anxiety disorders in adults (protocol stage)

Paraprofessionals for anxiety and depressive disorders

Therapeutic touch for anxiety disorders

Therapist-delivered distance cognitive behavioural therapy for anxiety disorders in adults (protocol stage)

Transdiagnostic versus specific cognitive-behavioral treatments for adults with anxiety disorders (protocol stage)

Valerian for anxiety disorders

Agoraphobia (2)

Combined psychotherapy plus benzodiazepines for panic disorder

Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia

Generalized anxiety disorder (GAD) (4)

Antidepressants versus placebo for generalised anxiety disorder (GAD) (protocol stage)

Azapirones for generalized anxiety disorder

Hydroxyzine for generalised anxiety disorder

Psychological therapies for generalised anxiety disorder

Neurocirculatory asthenia (0)

Obsessive compulsive disorder (OCD) (6)

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents

Psychological treatments versus treatment as usual for obsessive compulsive disorder (OCD)

Second-generation antipsychotics for obsessive compulsive disorder

Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD)

Transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder

Panic disorder (10)

Antidepressants and benzodiazepines for panic disorder in adults

Antidepressants versus placebo for panic disorder in adults

Azapirones versus placebo for panic disorder in adults

Benzodiazepines versus placebo for panic disorder in adults

Pharmacological treatments in panic disorder in adults: a network meta-analysis (protocol stage)

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta-analysis

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults

Combined psychotherapy plus benzodiazepines for panic disorder

Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia

Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults

Phobic disorders (1)

Social phobia / Social anxiety disorder (SAnD) (1)

Pharmacotherapy for social anxiety disorder (SAnD)

Stress disorders, traumatic (21)

Combat disorders (0)

Post-traumatic stress disorders (PTSD) (19)

3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder (PTSD) in adults (protocol stage)

Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)

Couple and family therapies for post-traumatic stress disorder (PTSD)

Pre-deployment programmes for building resilience in military and frontline emergency service personnel

Internet-based cognitive and behavioural therapies for post-traumatic stress disorder (PTSD) in adults

Pharmacotherapy for post traumatic stress disorder (PTSD)

Pharmacological interventions for preventing post-traumatic stress disorder (PTSD)

Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD)

Multiple session early psychological interventions for the prevention of post-traumatic stress disorder

Present-centered therapy (PCT) for post-traumatic stress disorder (PTSD) in adults

Psychological debriefing for preventing post traumatic stress disorder (PTSD)

Psychological therapies for chronic post-traumatic stress disorder (PTSD) in adults

Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder

Psychological therapies for children and adolescents exposed to trauma

Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents

Psychological, social and welfare interventions for psychological health and well-being of torture survivors

Repetitive transcranial magnetic stimulation for post-traumatic stress disorder in adults (protocol stage)

Self-report screening instruments for post-traumatic stress disorder (PTSD) in survivors of traumatic experiences (protocol stage)

Sports and games for post-traumatic stress disorder (PTSD)

Traumatic stress disorders, acute (2)

Early pharmacological interventions for acute traumatic stress symptoms: a network meta-analysis (protocol stage)

Early psychological interventions to treat acute traumatic stress symptoms

Eating disorders (11)

All eating disorders (3)

Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders

Interventions for preventing eating disorders in children and adolescents

Self-help and guided self-help for eating disorders

Anorexia nervosa (4)

Antidepressants for anorexia nervosa

Family therapy approaches for anorexia nervosa

Individual psychological therapy in the outpatient treatment of adults with anorexia nervosa

Specific psychological therapies versus other therapies or no treatment for severe and enduring anorexia nervosa (protocol stage)

Binge-eating disorder (1)

Psychological treatments for bulimia nervosa and binging

Bulimia nervosa (3)

Antidepressants versus psychological treatments and their combination for bulimia nervosa

Antidepressants versus placebo for people with bulimia nervosa

Psychological treatments for bulimia nervosa and binging

Coprophagia (0)

Eating disorders not otherwise specified (EDNOS) (0)

Female athlete triad syndrome (0)

Factitious disorders (0)

Munchausen syndrome (0)

Munchausen syndrome by proxy (0)

Fatigue syndrome, chronic (2)

Cognitive behaviour therapy for chronic fatigue syndrome in adults

Exercise therapy for chronic fatigue syndrome

Impulse control disorders (3)

Firesetting behavior (0)

Pharmacological interventions for the treatment of disordered and problem gambling

Psychological therapies for pathological and problem gambling

Intermittent explosive disorder (0)

Kleptomania (0)

Trichotillomania (1)

Pharmacotherapy for trichotillomania

Mood disorders (141)

Affective disorders, psychotic (25)

Bipolar disorder (25)

Aripiprazole alone or in combination for acute mania

Electroconvulsive therapy for acute affective episodes in people with bipolar disorder (protocol stage)

Electroconvulsive therapy for preventing relapse and recurrence in bipolar disorder (protocol stage)

Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of qualitative evidence (protocol stage)

Family interventions for bipolar disorder

Haloperidol alone or in combination for acute mania

Interventions for helping people recognise early signs of recurrence in bipolar disorder

Interventions for the management of obesity in people with bipolar disorder (protocol stage)

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder

Lamotrigine in the maintenance treatment of bipolar disorder

Lithium for acute mania

Medicines for bipolar disorder in older people (protocol stage)

Olanzapine alone or in combination for acute mania

Olanzapine in long-term treatment for bipolar disorder

Omega-3 fatty acids for bipolar disorder

Oxcarbazepine for acute affective episodes in bipolar disorder

Oxcarbazepine in the maintenance treatment of bipolar disorder

Risperidone alone or in combination for acute mania

Risperidone in long-term treatment for bipolar disorder

S-adenosyl methionine (SAMe) for depression in adults

Tiagabine in the maintenance treatment of bipolar disorder

Tiagabine for acute affective episodes in bipolar disorder

Topiramate for acute affective episodes in bipolar disorder in adults

Valproate for acute mania

Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder

Cyclothymia (0)

Depressive disorder (105)

Depression, postpartum (8)

Antidepressants for preventing postnatal depression

Antidepressant treatment for postnatal depression

Antidepressant treatment for postnatal depression

Breastfeeding interventions for preventing postpartum depression (protocol stage)

Brexanolone and related neurosteroid GABA(A) positive allosteric modulators for postnatal depression (protocol stage)

Interventions (other than psychosocial, psychological and pharmacological) for treating postpartum depression (protocol stage)

Perinatal internet-based cognitive behavioural therapy for preventing postnatal depression (protocol stage)

Psychosocial and psychological interventions for treating postpartum depression

Depressive disorder, major (87)

'Third wave' cognitive and behavioural therapies versus other psychological therapies for depression

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression

Acupuncture for depression

Agomelatine versus other antidepressive agents for major depression

Alprazolam for depression

Alternating current cranial electrotherapy stimulation (CES) for depression

Amitriptyline for depression

Amitriptyline versus placebo for major depressive disorder

Antidepressants versus placebo for the depressed elderly

Antidepressants for depressed elderly

Antidepressants for depression in physically ill people

Antidepressants plus benzodiazepines for adults with major depression

Antidepressants versus placebo for depression in primary care

Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease

Behavioural and cognitive-behavioural therapy based self-help versus treatment as usual for depression in adults and adolescents (protocol stage)

Behavioural therapies versus other psychological therapies for depression

Behavioural therapies versus treatment as usual for depression (protocol stage)

Brexpiprazole versus placebo or other antidepressive agents for treating depression (protocol stage)

Citalopram versus other anti-depressive agents for depression

Collaborative care for depression and anxiety problems

Couple therapy for depression

Prevention of depression in adults with long-term physical conditions

Duloxetine versus other anti-depressive agents for depression

Electroconvulsive therapy for the depressed elderly

Electroconvulsive therapy for depression (protocol stage)

Electroconvulsive therapy for preventing relapse and recurrence in people with depression (protocol stage)

Escitalopram versus other antidepressive agents for depression

Esketamine for treatment-resistant depression in adults (protocol stage)

Cognitive behavioural therapy (CBT), third-wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents

Exercise for depression

Exercise in prevention and treatment of anxiety and depression among children and young people

Exercise for the treatment of anxiety in children and adolescents (protocol stage)

Factors that influence participation in physical activity for anxiety or depression: a synthesis of qualitative evidence (protocol stage)

Family therapy for depression

Fluoxetine versus other types of pharmacotherapy for depression

Fluvoxamine versus other anti-depressive agents for depression

Humanistic therapies versus other psychological therapies for depression (protocol stage)

Humanistic therapies versus treatment as usual for depression (protocol stage)

Interpersonal, cognitive analytic and other integrative therapies versus other psychological therapies for depression (protocol stage)

Interventions for helping people recognise early signs of recurrence in depression (protocol stage)

Interventions for preventing relapse or recurrence of major depressive disorder in adults in a primary care setting: a network meta-analysis (protocol stage)

Dance movement therapy for depression

Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder

Light therapy for non-seasonal depression

Lithium versus antidepressants in the long-term treatment of unipolar affective disorder

Continuation and maintenance treatments for depression in older people

Low dosage tricyclic antidepressants for depression

Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease

Milnacipran versus other antidepressive agents for depression

Mirtazapine versus other antidepressive agents for depression

Multimedia-delivered cognitive behavioural therapy versus face-to-face cognitive behavioural therapy for depression in adults (protocol stage)

Music therapy for depression

Newer generation antidepressants for depressive disorders in children and adolescents

New generation antidepressants for depression in children and adolescents: a network meta-analysis

Omega-3 fatty acid supplementation for depression in children and adolescents (protocol stage)

Omega-3 fatty acids for depression in adults

Paroxetine versus other anti-depressive agents for depression

Pharmacy-based management for depression in adults

Pharmacological and psychological interventions for depression in people with tuberculosis (protocol stage)

Pharmacological interventions for depression in adults with chronic hepatitis B or C (protocol stage)

Pharmacological treatment for psychotic depression

Postdischarge interventions for depression (protocol stage)

Prognostic models for predicting relapse or recurrence of major depressive disorder in adults

Psychodynamic therapies versus other psychological therapies for depression (protocol stage)

Psychodynamic therapies versus treatment as usual for depression (protocol stage)

Psychological therapies for depression in older adults residing in long-term care settings (protocol stage)

Psychological therapies for major depressive disorder and prolonged grief in bereaved adults (protocol stage)

Psychostimulants for depression

Psychotherapeutic treatments for older depressed people

Reiki for depression and anxiety

Relaxation for depression

S-adenosyl methionine (SAMe) for depression in adults

Screening and case finding instruments for depression

Second-generation antipsychotics for major depressive disorder and dysthymia

Sertraline versus other antidepressive agents for depression

St John's wort for major depression

The process and delivery of cognitive behavioural therapy (CBT) for depression in adults: a network meta-analysis (protocol stage)

Transcranial magnetic stimulation for treating depression

Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents

Active placebos versus antidepressants for depression

Tricyclic drugs for depression in children and adolescents

Tryptophan and 5-Hydroxytryptophan for depression

Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults

Venlafaxine versus other anti-depressive agents for depression (protocol stage)

Vilazodone for major depressive disorder in adults (protocol stage)

Vortioxetine for depression in adults

What are the best ways to help people with depression go back to work?

Dysthymic disorder (2)

Antidepressants for depression in physically ill people

Pharmacotherapy for dysthymia

Seasonal affective disorder (5)

Second-generation antidepressants for preventing seasonal affective disorder in adults

Light therapy for preventing seasonal affective disorder

Melatonin and agomelatine for preventing seasonal affective disorder

Psychological therapies for preventing seasonal affective disorder

Second-generation antidepressants for treatment of seasonal affective disorder

Antidepressants for depression in adults with HIV infection

Psychological therapies for treatment-resistant depression in adults

Magnetic seizure therapy for treatment-resistant depression

Unspecified (11)

Client feedback in psychological therapy for children and adolescents with mental health problems

Cognitive or behavioural interventions (or both) to prevent or mitigate loneliness in adolescents, adults, and older adults (protocol stage)

Counselling for mental health and psychosocial problems in primary care

Folate for depressive disorders

Inositol for depressive disorders

Interventions for mood, anxiety disorders or self-harm in young offenders (protocol stage)

Lithium for maintenance treatment of mood disorders

Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries

Psychological and social interventions for the promotion of mental health in people living in low- and middle-income countries affected by humanitarian crises (protocol stage)

Short-term psychodynamic psychotherapies for common mental disorders

Paraprofessionals for anxiety and depressive disorders

Neurotic disorders (0)

Self injurious behavior (18)

Self mutilation (9)

Pharmacological interventions for self-harm in adults

Pharmacological interventions for self-harm in adults

First responder, clinician, and non-clinical support staff knowledge, attitudes, and behaviours towards people presenting for emergency care following self-harm: a mixed evidence synthesis (protocol stage)

Interventions for self-harm in children and adolescents

Interventions for self-harm in children and adolescents

Interventions for mood, anxiety disorders or self-harm in young offenders (protocol stage)

Prevention of self-harm and suicide in young people up to the age of 25 in education settings (protocol stage)

Psychosocial interventions for self-harm in adults

Service users’ experiences of emergency care following an episode of self-harm: a mixed evidence synthesis (protocol stage)

Pharmacological interventions for self-harm in adults

Interventions for self-harm in children and adolescents

Interventions for self-harm in children and adolescents

Means restriction for the prevention of suicide: generic protocol (protocol stage)

Means restriction for the prevention of suicide by jumping

Means restriction for the prevention of suicide on roads

Prevention of self-harm and suicide in young people up to the age of 25 in education settings (protocol stage)

Prevention of suicide in university and other post-secondary educational settings

Psychosocial interventions for self-harm in adults

Sexual and gender disorders (2)

Sexual dysfunctions, caused by medication (1)

All sexual dysfunctions (1)

Strategies for managing sexual dysfunction induced by antidepressant medication

Erectile dysfunction (0)

Sexual dysfunctions, psychological (1)

Interventions for vaginismus

Sleep disorders (13)

Jet lag syndrome (2)

Melatonin for the prevention and treatment of jet lag

Pharmacological interventions for jet lag (protocol stage)

Sleep initiation and maintenance disorders (primary insomnia) (11)

Acupuncture for insomnia

Antidepressants for insomnia in adults

Comparative efficacy and acceptability of pharmacological treatments for insomnia in adults: a systematic review and network meta-analysis (protocol stage)

Deprescribing of chronic benzodiazepine receptor agonists for insomnia in adults (protocol stage)

Eszopiclone for insomnia

Ramelteon for insomnia (protocol stage)

Remote non-pharmacologic interventions for sleep problems in adults during the COVID-19 pandemic (protocol stage)

Remote non-pharmacologic interventions for sleep problems in healthcare workers during the COVID-19 pandemic (protocol stage)

Zaleplon for insomnia (protocol stage)

Zolpidem for insomnia (protocol stage)

Zopiclone for insomnia (protocol stage)

Somatoform disorders (7)

Body dysmorphic disorders (1)

Pharmacotherapy and psychotherapy for body dysmorphic disorder

Conversion disorder (1)

Psychosocial interventions for conversion and dissociative disorders in adults

Hypochondriasis (1)

Psychotherapies for hypochondriasis

Neurasthenia (0)

Somatization disorder (2)

Pharmacological interventions for somatoform disorders in adults

Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults

Somatoform pain disorder (0)

Undifferentiated somatoform disorders (MUPS) (2)

Consultation letters for medically unexplained physical symptoms in primary care

Enhanced care by generalists for functional somatic symptoms and disorders in primary care

New and Updated (in the latest issue of the CLib):